當(dāng)前位置:首頁 > 產(chǎn)品中心 > 抗體/抗原 > 標(biāo)記一抗 > bs-0573R-FITCFITC標(biāo)記的周期素E抗體
簡要描述:Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are only expressed in tumors but not in normal tissue, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in the Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
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