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  • bs-0436P蛋白酶激活受體-2桔抗肽多肽

    Selective PAR2 peptide antagonist. Reverses taxol-induced mechanical allodynia, heat hyperalgesia and PKC activation in ICR mice. Blocks ERK activation and collagen production in isolated cardiac fibroblasts. Also reduces symptoms in a mouse model of dermatophyte-associated itch.

    更新時間:2025-02-26
    型號:bs-0436P
    廠商性質:生產廠家
    瀏覽量:49
  • bs-0071P神經肽Y封閉多肽

    This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting

    更新時間:2025-02-26
    型號:bs-0071P
    廠商性質:生產廠家
    瀏覽量:51
  • bs-11303P增食欲素B/欲激素B封閉多肽

    Prepro-orexin is 130 amino acid long peptide with a putative 33 AA secretory sequence, a hydrophobic core followed by residues with small polar side chains. The expression was detected in brain and to a small extent in testis. These neuropeptides bind and activate two closely related Orexin receptors—G-protein coupled receptors (GPCRs) OX1R and OX2R. Orexins (Orexin A and Orexin B) are a family of hypothalamic neuropeptides selectively expressed in the hypothalamus. Orexin A and Orexin B

    更新時間:2025-02-26
    型號:bs-11303P
    廠商性質:生產廠家
    瀏覽量:46
  • bs-0072P神經降壓素封閉多肽

    Neurotensin is a secreted tridecapeptide, which is widely distributed throughout the central nervous system, and may function as a neurotransmitter or a neuromodulator. It may be involved in dopamine-associated pathophysiological events, in the maintenance of gut structure and function, and in the regulation of fat metabolism. Tissue-specific processing may lead to the formation in some tissues of larger forms of neuromedin N and neurotensin. The large forms may represent more stable peptid

    更新時間:2025-02-26
    型號:bs-0072P
    廠商性質:生產廠家
    瀏覽量:58
  • bs-2265P酪酪肽封閉多肽

    $nPeptide tyrosine tyrosine (PYY) was originally isolated from porcine gut, which exhibits striking sequence homology with members of the pancreatic polypeptide family, including neuropeptide tyrosine (NPY). The peptide is localized to enteroglucagon containing (L/EG) and pancreatic (A) cells in many mammalian and non-mammalian species. PYY gene expression is upregulated by various growth factors, including growth hormone and insulin-like growth factor and the physiological effects of PYY

    更新時間:2025-02-26
    型號:bs-2265P
    廠商性質:生產廠家
    瀏覽量:51
  • bs-11280P內皮素2封閉多肽

    The endothelin (ET) family of proteins, which includes ET-1 (endothelin-1), ET-2 (endothelin-2) and ET-3 (endothelin-3), are vasoactive peptides that are involved in various functions throughout the body. Endothelins can affect the central nervous system and neuronal excitability, and they elicit potent vasoconstrictor action. While ET-1 is a potent, 21-amino acid vasoconstrictor peptide, ET-2 has the most potent vasoconstrictor activity. ET-3 functions as a ligand for endothelin receptor ty

    更新時間:2025-02-26
    型號:bs-11280P
    廠商性質:生產廠家
    瀏覽量:66
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