前列腺素E合成酶2抗體 The protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2.
端粒酶逆轉錄酶抗體 端粒酶逆轉錄酶hTERT是構成端粒酶的組分之一,是端粒酶活性的必需和限速成分,水平決定細胞端粒酶的活性。抑制hTERT可降低端粒酶的活性,從而抑制瘤細胞生長。目前對hTERT的研究已成為端粒酶研究的熱點問題,已發(fā)現(xiàn)TERT蛋白表達在腫瘤診斷中有重要意義,并制備了hTERT抗體及應用核酶技術等來抑制hTERT蛋白的表達,抑制端粒酶活性,從而抑制腫瘤的生長。
B細胞遷移基因2抗體 BTG2 is a member of the BTG/Tob family. This family has structurally related proteins that appear to have antiproliferative properties.
基質金屬蛋白酶-2抗體 基質金屬蛋白酶(matrix metalloproteinases, MMPs)MMP2是一族依賴鋅離子而降解各種細胞外基質的蛋白酶,亦稱IV型膠原酶或稱明膠酶A,其主要功能為降解IV型膠原,因而它在腫瘤細胞突破基底膜屏障和浸潤轉移中起重要作用。目前主要用于各種惡性腫瘤(如乳腺癌、胃腸道癌、卵巢癌、膀胱癌等)中的基底膜檢測與轉移浸潤的研究。
干擾素調節(jié)因子7抗體 IRF7 encodes interferon regulatory factor 7, a member of the interferon regulatory transcription factor (IRF) family.
HER2受體(N端)抗體 This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases.